The spontaneous, sporadic and sometimes unpredictable nature of children's physical activity causes fluctuations in blood glucose level and challenges for children with type 1 diabetes. Physical activity monitoring has potential utility. This study aimed to explore the perceptions of physical activity monitoring among healthcare professionals and assess the feasibility and acceptability of using it in the management of paediatric type 1 diabetes.
Diabetes mellitus (DM) is associated with an elevated risk of various cancers, among which is colorectal cancer (CRC). Similarly, pre-existing DM may also influence prognosis among patients with CRC. We have performed a systematic review and meta-analysis to assess the association between DM and risk of death and relapse after a diagnosis of CRC.
To bridge the gap between existing clinical evidence and recommendations around screening for diabetes-related distress (DD) and the observation of a low level of adoption of these suggestions in everyday clinical practice. We focused on the use of the Diabetes Distress Scale (DDS) by adult diabetes care specialists.
The current screening method for diabetic nephropathy (DN) is based upon detection of albumin in the urine and decline of glomerular filtration rate. The latter usually occurs relatively late in the course of the disease. A polygenic risk score (PRS) was recently developed for early prediction of the risk for type 2 diabetes (T2D) patients to develop DN. The aim of this study was to assess the economic impact of the implementation of the PRS for early prediction of DN in T2D patients, compared to usual screening methods, in Canada.
Postpartum mothers with gestational diabetes may remain with either type-2 diabetes mellitus, impaired glucose tolerance or impaired fasting glucose. Our objective was to identify maternal variables that could predict one or more of these conditions.
In this study, we conducted a scoping review to identify the prevalence of both depression and diabetes distress in patients with type 2 diabetes in low- and middle-income countries in South Asia.
Our aim in this study was to determine whether a cognitive-behavioural therapy plus small changes lifestyle intervention can produce comparable improvements in insulin users vs patients not using insulin with uncontrolled type 2 diabetes (T2D) and comorbid depressive or regimen-related distress (RRD) symptoms.
Given the high incidence of hyperglycemia and hypoglycemia in hospital and lack of prediction tools for this problem, we developed a clinical tool to assist early identification of individuals at risk for persistent adverse glycemia (AG) in hospital.
Alcohol consumption has serious potential consequences for persons with type 1 diabetes. This cross-sectional study examined associations between drinking status and diabetes-related outcomes.
Copy number variations (CNVs) are large-scale deletions or duplications of DNA that have required specialized detection methods, such as microarray-based genomic hybridization or multiplex ligation probe amplification. However, recent advances in bioinformatics have made it possible to detect CNVs from next generation DNA sequencing (NGS) data. Maturity Onset Diabetes of the Young (MODY) 5 is a subtype of autosomal dominant diabetes that is often caused by heterozygous deletions involving the HNF1B gene on chromosome 17q12.
Guidelines for safe exercise strategies exist for both pediatric and adult patients living with type 1 diabetes. The management of type 1 diabetes during exercise is complex but making insulin dosing adjustments in advance of activity can yield positive outcomes and reduce the likelihood of hypoglycemia. Closed loop (also known as automated insulin delivery) systems are able to partially automate insulin delivery and can assist in exercise and overall management of type 1 diabetes. Current exercise guidelines, however, focus primarily on management strategies for patients using multiple daily injections or open loop insulin pump therapy.
to develop the first theory that explains the processes of engagement in self-care management for adults with diabetic foot ulcer (DFU).
Our aim in this study was to investigate how patients’ perceptions of their diabetes health-care providers’ (HCP) age, gender and ethnicity impact shared decision-making using the Theory of Planned Behaviour.
To assess impact of the Mobile Diabetes Telemedicine Clinic, which serves First Nations communities in British Columbia, on diabetic clients’ condition and management.
Polycystic ovary syndrome (PCOS) is a common reproductive/metabolic condition associated with obesity, type 2 diabetes (T2D) and depression in adult women. Depression in adults is related to PCOS dermatologic manifestations. Adolescents with obesity with or without T2D have elevated depression symptoms, but data from youth with PCOS and obesity with/without T2D are limited.
The best nutritional practices for exercise and sports performance are largely activity specific. The presence of type 1 diabetes undeniably bestows additional factors to consider to manage exercise and ensure adequate nutrients and fuels are available for optimal performance. Whether participating in sports or physical activity on a recreational basis or striving to achieve a high level of athletic performance, individuals with type 1 diabetes must pay attention to their nutritional and dietary patterns, including intake of macronutrients, micronutrients, fluids and supplements, such as caffeine to maintain metabolic and glycemic balance.
It is well known that exercise can improve the glycemic profile in individuals with type 2 diabetes (T2D). However, the optimal timing of exercise is often debated. Our aim in this study was to compare the effects of exercise performed at different times of the day and different timing in relation to meals on 24-hour glucose profiles in people with T2D.
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