1 month ago
Although food skills and literacy programs have been well assessed in healthy populations, they have been inadequately evaluated in children with type 1 diabetes (T1D). Summerlunch+ is a Toronto-based 8-week virtual program that teaches cooking, nutrition, and sustainability. Through questionnaires, the study aims to assess the impact of this program on food literacy in children with diabetes.
JOEIE SCHWARTZ, OLIVIA CHOW, SARAH GOLDSTEIN, VANITA PAIS, SUSAN WRIGHT, ENZA GUCCIARDI
1 month ago
Post-hoc analyses of randomized controlled trials have suggested a beneficial effect of glucagon-like peptide 1 receptor agonists (GLP-1RA) on dementia. Where real-world evidence has been limited, we conducted a propensity score-matched, retrospective cohort study to investigate the relationship between new use of GLP-1RA and dementia.
FABIO CASTRILLON-RAMIREZ, JENNIFER REID, KEVIN YAU, BLAYNE WELK, KRISTIN CLEMENS
1 month ago
Rationale: Insulin resistance, hyperandrogenemia, and other adverse metabolic markers have been associated with infertility, especially in women with obesity. However, few studies have examined the associations between longitudinal changes in blood markers and fertility outcomes in women with obesity and infertility.
CHRISTOPHE RICHER DIT LAFLÈCHE, ALEXANDRA THIBODEAU, GÉRARD NGUETA, MATEA BELAN, FARRAH JEAN-DENIS, MARIE-FRANCE LANGLOIS, MARIE-HÉLÈNE PESANT, BELINA CARRANZA MAMANE, JEAN-PATRICE BAILLARGEON
1 month ago
Prevalence of prediabetes and type 2 diabetes continues to grow. Early identification of individuals at risk for diabetes and detection of prediabetes or diabetes is crucial for timely intervention and subsequent reduction in complications.
MOUSTAFA ELLITHY, LORI LEBLANC, AARTI PATEL, INSUN CHO, NADEEM ABJI
1 month ago
To develop an individualized and scalable digital intervention to improve diabetes self-efficacy of young adults (YA) as they transition to adult type 1 diabetes (T1D) care.
RAYZEL SHULMAN, MADISON TAYLOR, NOOR EL-DASSOUKI, KAYLEN PFISTERER, PEDRO ELKIND VELMOVITSKY, MERANDA NAKHLA, MARLEY GREENBERG, ALANNA LANDRY, GEETHA MUKERJI, ELISE MOK, ANNE-SOPHIE BRAZEAU, LAURA DESVEAUX, JESSICA KICHLER, MIKAYLA SONNENBERG, ASHISH…
1 month ago
Acute complications of type 1 diabetes (T1D) can affect brain structure and function due to increased oxidative stress and energy deprivation in neurons. However, studies show mixed results regarding the relationship between T1D and cognitive skills.
DORSA ARMAN, LUC VAN HEERDEN, TY SIDEROFF, JANE JUN, CHRISTINE VOSS
1 month ago
Optimal diabetes management in school is a prerequisite for learning and minimizing risk of complications. Students should be supported to use their preferred insulin regimen, including multiple daily injections (MDI) with lunch-time insulin. We describe the development, roll-out, and ongoing quality improvement (QI) of a provincial policy and tools/resources supporting lunch-time insulin injections by trained Teacher Assistants (TA).
FRAN BOWDEN, LISA GARAND, ANDREA WATERS, DARREN HALEY, ELIZABETH CUMMINGS
1 month ago
In Canada, retinopathy screening for individuals living with diabetes is completed according to treatment guidelines in approximately 70% of people. Identification of individuals in need of screening, especially for underserved systematically marginalized populations, is challenging in the absence of a diabetes registry.
JAMES BOWEN, ALEKSANDRA VUKOBRADOVIC, JUDY HUNG, JENNIFER RAYNER, SARA BHATTI, CONRAD POW, SUJA MATHEW, DEBBIE SISSMORE, MALCOLM SISSMORE, ANUISA RANJAN, MARIA CONSUELO CENIZAL, MAUREEN GANS, M. PHILLIPS, REBECCA MERRITT, MICHAEL BRENT, VALERIA RAC
1 month ago
Patients with rare familial chylomicronemia syndrome (FCS) and relatively common multifactorial chylomicronemia syndrome (MCS) both present with severe hypertriglyceridemia, defined as plasma triglyceride concentration ≥10 mmol/L (≥885 mg/dL). Clinically, there can be confusion between the 2 conditions.
CATHERINE SPAGNUOLO, ROBERT HEGELE, JIAN WANG, ADAM MCINTYRE, BROOKE KENNEDY
1 month ago
Adults with type 2 diabetes not on insulin are under-represented in trials examining the effectiveness of continuous glucose monitoring (CGM).
DARREN LAU, ROSEANNE YEUNG, DONNA MANCA, PRATIMA SINGH, TAWNYA PERRY, INGA OLU-JORDAN, JIAWEI RYAN ZHANG, GULELALA RAHIM, EVAN HAGEN
1 month ago
Adults who use insulin to treat diabetes may self-administer multiple daily injections or use an insulin pump. Patients must weigh pros and cons of each insulin delivery method and make a quality decision (e.g., informed and value congruent). The overall aim was to evaluate the change in decisional needs after providing decision coaching and a patient decision aid (PtDA) for those considering an insulin pump.
SANDHYA GOGE, AMEL ARNAOUT, DOMINIQUE GENDRON, DAWN STACEY
1 month ago
Evidence that type 2 diabetes (T2D) remission can be achieved by combining nutrition, physical activity, and intensive metabolic and pharmacotherapy strategies is now challenging the traditional management paradigm. Remission interventions appear promising; however, their acceptance and implementation have been limited in real-world settings with diverse populations. Furthermore, T2D remission strategies may evoke feelings of shame and stigma. Little is known about practical, person-centred strategies that can support individuals undergoing T2D remission.
DIANA SHERIFALI, MEGAN RACEY, JULIE MAKARSKI, MONIKA KASTNER
1 month ago
Molecular testing (MT) of cytologically indeterminate thyroid nodules (ITNs) did not impact thyroidectomy rates in the USA. We therefore evaluated MT as an adjunct to an optimized integrated interdisciplinary thyroid nodule diagnostic pathway.
JIAHUI WU, PAUL STEWARDSON, MARKUS ESZLINGER, MOOSA KHALIL, SANA GHAZNAVI, ERIK NOHR, ADRIAN BOX, RALF PASCHKE
1 month ago
The rate of diabetic ketoacidosis (DKA) at diagnosis of type 1 diabetes in children was 38.9% in an international study in 2021 and 55% in a Canadian study in 2020. The Canadian Pediatric Endocrine Group is developing a scalable and equitable intervention to prevent DKA at diagnosis in Canada.
RAYZEL SHULMAN, ZEENAT LADAK, MIKAYLA SONNENBERG, ELIZABETH CUMMINGS, ELLEN GOLDBLOOM, MARK INMAN, MANPREET DOULLA, ELIZABETH SELLERS, DIANE WHERRETT, PATRICIA LI, MERANDA NAKHLA, VALERIA RAC, GENEVIEVE ROULEAU, JENNIFER SHULDINER, CELIA LAUR
1 month ago
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting females of reproductive age. Administrative health data provide researchers the opportunity to assess PCOS health outcomes in the population; however, variable administrative health data case definitions have been used. Our aim was to develop and validate a PCOS case definition for use in administrative health data. We performed a retrospective cohort study and reviewed 3,951 electronic health records of females aged 18–45 years who presented at the Foothills Medical Center Gynecology Clinic in Calgary, Alberta between January 2014 to December 2019.
JENNA SALEM, ROBYN SHOULDICE, JENNIFER YAMAMOTO, SHEFFINEA KOSHY, TYRONE HARRISON, PAUL RONKSLEY, AMY METCALFE, ERIN BRENNAND, JAMIE BENHAM
1 month ago
Purpose: This study aims to develop a primary care clinical and patient pathway that assists primary care providers and patients to improve the diagnosis and management of polycystic ovary syndrome (PCOS), and to address the health needs of those with PCOS.
DONNA VINE, MAHUA GHOSH, MAGGIE MCPHERSON, SARAH CHAMBERS, LYDIA SADIQ, JULIE ROBINSON, PAULA BECKLES, TAREK MOTAN, LAURIE MEREU, BEATE SYDORA, CAROLINE LEJOUR, BETTINA LOTT, ADERONKE ACHI
1 month ago
Sixteen per cent of Canadians currently live with prediabetes, putting them at elevated risk of type 2 diabetes (T2D). The 2021 National Framework for Diabetes has prioritized improved surveillance for patient level factors and associated clinical outcomes to gain a deeper understanding of disease progression. There is lack of knowledge about the provision of diabetes prevention care across Canada. Understanding what resources are available and how these resources, or lack thereof, differ across Canada is imperative for future population level initiatives.
JESSICA BOURNE, RENEE YOUNG, JOSEPH KELLY, MARY E. JUNG
1 month ago
Diabetes medication deintensification is a strategy to minimize risk of medication harms and lower treatment burden, which is particularly appropriate for long-term care (LTC) residents. We aimed to evaluate diabetes deintensification practices among newly admitted Ontario LTC residents.
JIM CHEN, WADE THOMPSON, LISA MCCARTHY, SHO PODOLSKY, PAULA ROCHON, CELESTE FUNG, EMILY MCDONALD, ANDREA GRUNEIR, ILIANA LEGA
1 month ago
Monitoring individuals with diabetes mellitus (DM) in long-term care (LTC) settings is challenging due to limited guidelines and potential for unnecessary testing. We evaluated diabetes testing rates and patterns among LTC residents in Ontario, Canada.
YOUSSEF EL-SAYES, SHO PODOLSKY, WADE THOMPSON, LISA MCCARTHY, ILIANA LEGA
1 month ago
We sought to assess the current practice of Canadian pediatric endocrinologists with respect to screening for diabetic kidney disease (DKD), comfort in interpreting markers of kidney function, and identifying barriers and facilitators to the uptake of a novel, pediatric T2D-specific estimated glomerular filtration (eGFR) formula.
PAUL RYAN, EDGAR DELBERT, MELISSA DEL VECCHIO, CARRIE COSTELLO, JILL HAMILTON, BRANDY WICKLOW, ALLISON DART
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