1 week 1 day ago
Attainment of the A1C target of ≤7.0% is consistently low among those living with type 1 diabetes (T1D). We evaluated endocrinologists’ acceptability and implementation of A1C targets.
Sanchit Kaushal, Patience Fakembe, Ilana J. Halperin, Gillian A. Hawker, Alanna Weisman
1 week 2 days ago
Saad Khan, Fatima Naveed, Ayesha Khan, Rizwan Ahmad, Faraz Arshad
3 weeks 6 days ago
To describe a type 1 diabetes melllitus (T1DM) transition care model by assessing clinic attendance, glycemic management, and diabetes-related hospitalizations.
Samantha Jacobson, Isabella Albanese, Jonathan-Raphaël Stetco, Natasha Garfield
3 weeks 6 days ago
Mirna Gerges, Meredith Chiasson, Carly Nichols, Nancy Morrison, Barna De
4 weeks ago
Diabetes duration is an underappreciated risk factor in type 2 diabetes (T2DM) management that can increase the risk of complications and potentially decrease the effectiveness of lifestyle interventions. However, whether T2DM duration impacts the efficacy of an elastic band resistance training intervention for older adults living with comorbid T2DM and frailty is unclear.
Amy M. Thomson, Isaac C. Cull, Logan E. Peskett, Danielle R. Bouchard, Martin Sénéchal
4 weeks 1 day ago
Maha Lebbar, Anne Bonhoure, Rémi Rabasa-Lhoret, Zekai Wu
1 month 2 weeks ago
The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated.The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies/article-withdrawal.
Jill Trinacty, Ronald M. Goldenberg
1 month 3 weeks ago
This study aimed to describe trends in incidence of gestational diabetes in Manitoba and within subgroups that often experience health inequities.
Nicole M. Brunton, Kevin Friesen, Jennifer M. Yamamoto, Heather J. Prior, Jonathan McGavock
1 month 3 weeks ago
Our aim in this study was to identify how to improve diabetic retinopathy screening from the perspectives of people with type 2 diabetes and health-care professionals and to elicit their thoughts on initiatives to increase attendance.
Gabriela B. Petersen, Lene E. Joensen, Jette K. Kristensen, Henrik Vorum, Stine Byberg, Mia V. Fangel, Bryan Cleal
1 month 3 weeks ago
Previous reviews have highlighted the efficacy of lifestyle diabetes prevention programs (DPPs) in decreasing type 2 diabetes (T2D) risk, but the participating populations were predominantly white. This is concerning as ethnically diverse populations are disproportionately affected by T2D. The objective of this scoping review was to: 1) summarize existing tailored DPPs and 2) provide recommendations for future program implementation to improve access and reach for diverse populations.
Cara E. Johnston, Megan M. MacPherson, Mary E. Jung
2 months ago
The aim of the study was to compare cardiac and respiratory function at rest in participants with early-onset type 2 diabetes and a control group without diabetes, matched for age, sex, and body mass index (BMI).
Phillip A. Munoz, David S. Celermajer, Yu Gu, Sue Bradley, Jencia Wong, Maria I. Constantino, Sue McLennan, Edmund M.T. Lau, Jennifer A. Alison, Alison R. Harmer
2 months 1 week ago
Indigenous peoples in Canada are considered the highest risk populations for type 2 diabetes mellitus (T2DM). Quality improvement (QI) strategies may be considered effective interventions for improving T2DM health outcomes. The purpose of this study was to understand experiences associated with implementation of the SOAR QI program to improve prevention and management of T2DM.
Melanie Dissanayake, Romina Pace, Stewart Harris
2 months 2 weeks ago
Activating transcription factor 4 (ATF4) and mean amplitude of glycemic excursion (MAGE) have been implicated in the pathogenesis of osteoporosis (OP) and type 2 diabetes mellitus (T2DM). In this retrospective cohort study we assessed the predictive value of serum ATF4 and MAGE for occurrence of OP in patients with T2DM.
Jing Zhang, Wei Huang
2 months 3 weeks ago
Women with gestational diabetes (GDM) are advised to undergo an oral glucose tolerance test (OGTT) within 6-months postpartum, owing to their elevated risk of developing pre-diabetes/diabetes. However, the optimal approach to glycemic surveillance in the years thereafter is unclear. We thus sought to compare OGTT and A1C for chronic monitoring of women with previous GDM.
RAVI RETNAKARAN, JIAJIE PU, ANTHONY HANLEY, BERNARD ZINMAN
2 months 3 weeks ago
In type 2 diabetes (T2D), formation of toxic protein aggregates named amyloid in pancreatic islets contributes to islet inflammation, and beta-cell dysfunction and death, by promoting IL-1beta production and activation of the Fas-mediated apoptotic pathway. Islet macrophages are the main source of amyloid-induced IL-1beta production. We examined the effects of amyloid formation on pro-inflammatory (M1) and anti-inflammatory (M2) islet macrophages.
DANISH MALHOTRA, JANESSA SAWATZKY, LUCY MARZBAN
2 months 3 weeks ago
Addressing the disproportionate rates of type 2 diabetes (T2D) among Indigenous peoples in Canada requires innovative, community-engaged efforts. Through a multi-phase study, our team of researchers, clinicians, Knowledge Keepers, people with Indigenous living experience, and community representatives is collaboratively developing strategies for promoting health and wellness among Indigenous youth with an aim to prevent T2D. The overall research purpose is to co-design culturally-informed, community-specific educational resources that support healthy living and T2D prevention among youth.
SHELLEY SPURR, MERIDITH BURLES, JILL BALLY, ALLISON CAMMER, CATHY LANGDON
2 months 3 weeks ago
In 2022, the FDA approved the anti-CD3 immunotherapy teplizumab to delay symptomatic type 1 diabetes (T1D), although the mechanism involved remains unclear. Evidence shows some β cells escape death and instead undergo senescence during T1D. This study aimed to determine whether anti-CD3, which mitigates β-cell destruction by cytotoxic T cells, also impacts senescent β-cell accumulation during T1D.
JASMINE PIPELLA, NAYARA RAMPAZZO MORELLI, PETER THOMPSON
2 months 3 weeks ago
Latent autoimmune diabetes of adults (LADA), characterized by gradual autoimmune destruction of beta cells that spans between type 1 and type 2 diabetes, currently lacks a comprehensive assessment for diabetes distress.
MAYA NEHME, MOHAMAD ISSA, ANNE-SOPHIE BRAZEAU, AMELIE ROY-FLEMING, SARAH HAAG, NADINE TALEB, CATHERINE LEROUX
2 months 3 weeks ago
Endothelial dysfunction, central to the development of chronic diabetic complications, often manifests in the form of endothelial-to-mesenchymal transition (EndMT), where endothelial cells lose their endothelial properties and adopt mesenchymal-like phenotypes. miR-9 is a key regulator of glucose-induced EndMT in the retina and heart, however, the relation between high glucose and miR-9 suppression remains unclear. We hypothesized that despite playing a key role in EndMT in both organs, the regulatory linkage between high glucose and miR-9 inhibition differ between the retina and heart.
ERIC WANG, BIAO FENG, SUBRATA CHAKRABARTI
2 months 3 weeks ago
Patient decision aids (PtDAs) are evidence-based interventions designed to help patients make informed health decisions aligned with their values and preferences. The aim of this sub-analysis was to evaluate the effectiveness of PtDAs for adults facing diabetes-related screening, prevention, and treatment decisions.
SANDHYA GOGE, CHRISTOPHER TRAN, DAWN STACEY, KRYSTINA LEWIS, MEG CARLEY, CAROL BENNETT
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23 minutes 6 seconds ago
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