2 days 4 hours ago
To compare two gestational diabetes mellitus (GDM) diagnostic thresholds in relation to large for gestational age (LGA) status and secondary adverse pregnancy outcomes.
Sanaz Azizi, Agnieszka Majdan, Rachel Bond, Natasha Garfield, Sara Meltzer, Shaun Eintracht, Kathryn Morrison, Julia Ma, Kaberi Dasgupta, Tricia Peters
2 days 4 hours ago
Baiju R. Shah, Kimberley Hanson, Gillian L. Booth, Sonia Butalia, Ghazal S. Fazli, Calvin Ke, Lorraine L. Lipscombe, Meranda Nakhla, Brandy Wicklow, Roseanne O. Yeung, Kaberi Dasgupta, Canadian Diabetes Epidemiology Group
6 days 4 hours ago
Interest in incretin therapy for type 1 diabetes is increasing, but data lacks regarding patient-reported outcomes and personal experience in this population with this drug.
Melissa-Rosina Pasqua, Joelle Doumat, Michael A. Tsoukas, Ahmad Haidar
1 week 3 days ago
Assess the effect of a 6-week continuous glucose monitor (CGM) intervention with telemonitoring-enabled virtual diabetes educator visits on patient-reported outcomes (PROs) in adults with type 2 diabetes (T2D) not using insulin.
Inga Olu-Jordan, Pratima Singh, Jiawei Ryan Zheng, Roseanne O. Yeung, Donna P. Manca, Tawnya Perry, Gulelala Rahim, Evan Hagen, Darren Lau
1 week 6 days ago
Subcutaneous (SC) insulin has been studied as an alternative to intravenous (IV) insulin to reduce resource consumption in the management of diabetic ketoacidosis (DKA). However, the feasibility and safety of an SC protocol has not been demonstrated in a Canadian context.
Judy K. Qiang, Alex Kiss, Wanqing Yu, Andre Carlos Kajdacsy-Balla Amaral, Dominick Shelton, Lowyl Notario, Ilana Halperin
3 weeks 2 days ago
To quantify the health benefit costs associated with type 2 diabetes mellitus (T2D) among employees aged 40-59 years in Canadian employer-sponsored benefit plans.
Godfrey Mau, Julie Hviid Hahn-Pedersen
3 weeks 4 days ago
Type 2 diabetes (T2D) and knee osteoarthritis (OA) frequently co-occur, and concomitant knee OA increases risk for diabetes complications. Despite this, OA is frequently undertreated. Diabetes health professionals’ (HPs’) perceptions of the impact of knee OA in people with T2D may impact how it is addressed in clinical practice. We aimed to understand how diabetes HPs perceive the impact of knee OA on diabetes management and outcomes.
Joy Du, Esther J. Waugh, Rebecca Voth, Crystal MacKay, Ian Stanaitis, Gillian A. Hawker, Lorraine L. Lipscombe, Lauren K. King
4 weeks ago
To examine postpartum diabetes screening and rates in women diagnosed with gestational diabetes mellitus (GDM) using standard versus modified criteria during the COVID-19 pandemic.
Sonia Butalia, Olesya Barrett, Anamaria Savu, Vichy Liyanage, Peter Senior, Roseanne O. Yeung, Padma Kaul
1 month ago
Globally, the prevalence of Type 2 Diabetes (T2D) among adolescents is increasing. While T2D is known to bring physical health challenges, less is known about adolescents’ psychosocial experiences of T2D. We aimed to identify and synthesize existing qualitative research about adolescents’ psychosocial experiences of T2D to inform healthcare recommendations.
Melissa Oxlad, Lorraine Smith, Tyla McNamara, Ashley Young, Ella Borrowdale, Alexia Pena
1 month 1 week ago
Rates of type 1 and type 2 diabetes (T1D and T2D, respectively) in youth may be increasing globally, but findings vary across populations. We aimed to determine changes in incidence and prevalence of T1D and T2D over a 25-year period (1994–2018) in youth <20 years of age in Nova Scotia (NS).
Elizabeth A. Cummings, Teresa Pinto, O. Maya Rao, Pamela Talbot
1 month 2 weeks ago
Delayed diagnosis of diabetes in children can lead to diabetic ketoacidosis, a life-threatening condition occurring in 10% to 80% of children at diabetes diagnosis. Ketoacidosis is preventable with prompt recognition of signs, urgent attendance to care, and rapid diagnosis and management. Our aim in this study was to plan for the development of an intervention to recognize signs of diabetes in children and prevent ketoacidosis that is evidence and theory informed and has potential for widespread implementation and long-term impact across Canada.
Zeenat Ladak, Priscilla Medeiros, Geneviève Rouleau, Jennifer Shuldiner, Shazhan Amed, Elizabeth Cummings, Manpreet Doulla, Josephine Ho, Mark Inman, Sarah E. Lawrence, Patricia Li, Elizabeth Moreau, Meranda Nakhla, Julia Von Oettingen, Elizabeth Sellers…
1 month 3 weeks ago
To develop a machine learning model that accurately predicts the risk of acquiring COVID-19 in community-dwelling adults with type 1 and/or type 2 diabetes in Alberta, Canada.
Dean T. Eurich, Darren Lau, Weiting Li, Olivia Weaver, Tanya Joon, Ming Ye, Finlay A. McAlister, Padma Kaul, Salim Samanani
1 month 3 weeks ago
Physical activity (PA) is a critical component of diabetes management, resulting in lower glycated hemoglobin (A1C) levels [1,2] and reduced risk of complications and comorbidities [3,4]. Despite this, most people living with diabetes do not meet current guidelines [5,6]. Although adherence to regular PA is challenging across all populations, those with diabetes may face specific barriers toward PA adoption and maintenance. Notably, these barriers may also vary according to diabetes type, as individuals who have type 1 or type 2 diabetes (T1D and T2D, respectively) may experience unique challenges.
Lindsay S. Nagamatsu, Joyla A. Furlano, Samantha Marshall, Olivia Ghosh-Swaby, Gillian Rutherford, Jane Yardley
2 months 3 weeks ago
Social determinants of health (SDH) impact diabetes outcomes. In response to the COVID-19 pandemic, virtual care ensured health care access. However, socially disadvantaged groups have less technology access and skills, leading to potential disparities. We assessed the association between SDH and virtual visit success in children living with diabetes.
Laurence Bastien, Ellen B. Goldboom, Ewa Sucha, Richard J. Webster, Ivan Terekhov, Caroline Zuijdwijk
2 months 3 weeks ago
Published data still highlighted discordances between glucose management indicator (GMI; the parameter estimating glycated hemoglobin [A1C] from continuous glucose monitoring [CGM] reporting) and laboratory A1C, for reasons yet to be explored. In our study we aimed to identify potential clinical factors contributing to these discordances.
Grażyna Deja, Aleksandra Brudzińska, Łukasz Wybrańczyk, Rafał Deja, Przemysława Jarosz-Chobot
3 months ago
Diabetes and prediabetes are associated with premature death and are recognized as conditions of accelerated biologic aging. To date, the best measurement of biologic age is chronologic age. Measures of biologic age that can replace chronologic age as a predictor of death can better approximate risk in affected individuals.
Hertzel C. Gerstein, Guillaume Pare, Keyun Zhou, Serena Yang, Michael Chong, Gregory R. Steinberg, Shun Fu Lee
3 months 1 week ago
The rising incidence of type 2 diabetes (T2D) among Indigenous peoples, exacerbated by historical injustices and health inequities, underscores the need for culturally-sensitive health interventions that address both the physiological and psychological burdens of diabetes. This research protocol describes a community-driven initiative aimed at enhancing diabetes management among Indigenous youth and young adults in Canada, leveraging the lived experience and leadership of Indigenous young adults.
Sahar Fazeli, Jonathan Linton, Paul Linton, Lucy Trapper, Catherine Godin, Helene Porada, Deborah Da Costa, Kaberi Dasgupta, Isabelle Malhame, Claudia Mitchell, Elham Rahme, Julia Elisabeth Von Oettingen, Romina Pace
3 months 1 week ago
Trials using intensive lifestyle interventions have demonstrated remission of type 2 diabetes mellitus (T2DM), but data on real-world clinical approaches remain limited.
Christopher Gudas-Cantin, Valérie Dionne, Élise Latour, Karine Lamoureux, Lyne Chevrefils, Chantal Gariepy, Marie-Hélène Morissette C, Lina Mokdad, Juliette Morin, Sarah-Maude Martin, Mathieu Gayda, Florent Besnier, Sara Desmarais, Anil Nigam, Philippe L…
3 months 1 week ago
Kara Hawker, Justin Morein, Gurleen Gill, Irena Druce
3 months 2 weeks ago
Glucagon-like peptide 1 receptor agonists (GLP1-RAs), a relatively new class of drugs, are used widely in treating type 2 diabetes mellitus and obesity. Maintaining long-term glycemic control lowers the risk of development and progression of diabetic retinopathy. However, recent literature has raised concerns about transient worsening of the condition with use of GLP1-RAs. In this review we evaluate the association between GLP1-RAs and retinopathy in patients with diabetes mellitus. We also analyzed the available evidence on the potential association between semaglutide therapy and nonarteritic anterior ischemic optic neuropathy (NAION).
Nadia Nadeem, Raghad Mazin Al Issa, Asnin Shah, Rahaf Wardeh, Fauzia Rashid, Elamin Ibrahim Abdelgadir, Alaaeldin Bashier
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