2 months 1 week ago
Gestational diabetes mellitus (GDM) increases future risks of type 2 diabetes and cardiovascular disease. Despite Diabetes Canada guidelines recommending postpartum glucose testing following GDM, uptake remains low. Canadian population-based studies are needed to examine systems-level factors affecting uptake.
Kathleen Baker, Nikki Stephenson, Colleen Cuthbert, Doreen Rabi, Amy Metcalfe
2 months 2 weeks ago
This study explores the link between circulating vitamin C levels and the risk of diabetes mellitus (DM) using data from the National Health and Nutrition Examination Survey (NHANES) for the cycles of 2003-2004, 2005-2006, and 2017-2018. Our analysis revealed a significant inverse relationship, showing that higher levels of vitamin C are associated with a reduced risk of DM. Specifically, higher vitamin C concentrations correlated with lower odds of DM, particularly at elevated quartile levels. Despite these findings, Mendelian randomization (MR) analysis did not establish a causal link between vitamin C and type 1 diabetes (T1DM).
Zhitong Li, Jinchang Liu, Xingyu Li, Shiwei Liu
2 months 3 weeks ago
People with diabetes are vulnerable to health inequities and population level COVID-19 vaccine uptake among adults with diabetes is unknown. Our aim was to assess COVID-19 vaccine uptake among adults with and without diabetes and the factors associated with vaccination.
Sonia Butalia, Ronald J. Sigal, Baiju R. Shah, Jamie L. Benham, Brandy Wicklow, Catherine H. Yu, Kaberi Dasgupta, Luan M. Chu, Shazhan Amed, Cora Constantinescu, Padma Kaul
2 months 3 weeks ago
To explore adolescents' experiences of T2D, particularly concerning (1) diagnosis and management and (2) emotional wellbeing.
Gitanjali Subramani, Alexia S. Peña, Melissa Oxlad
2 months 4 weeks ago
2 months 4 weeks ago
2 months 4 weeks ago
3 months ago
The South Asian population is rapidly growing in the Greater Toronto Area with a growth rate of 10.6% versus the national average of 5.2%. Diabetes disproportionately affects South Asians, 8.1 times higher compared to Caucasians with increased risk of macrovascular and microvascular complications. There are several risk factors that have been identified including 24 single nucleotide polymorphisms, higher insulin resistance, low mean skeletal mass with higher visceral fat, and socioeconomic and family stressors.
Anjali Thomas, Nirojini Sivachandran
3 months 1 week ago
Children and youth with type 1 diabetes (T1D) must have support to manage their condition at school. In 2017, Ontario students and their parents were surveyed to assess the level of school support and the extent to which that support met perceived needs. In 2018 a provincial policy was established, providing high level guidance regarding children with T1D in school. We redistributed our survey in 2023 to determine whether support for children with T1D has improved and where gaps remain.
Hannah Geddie, Ereny Bassilious, Myanca Rodrigues, Elizabeth Moreau, Mark R. Palmert, Sarah E. Lawrence
3 months 1 week ago
To determine the contemporary annual incidence rates of hospitalization for diabetes-related foot complication (DFC) and lower-extremity amputation in Canada.
Angela Y. Kim, James Hanley, Rebecca Fuhrer, Charles de Mestral
3 months 2 weeks ago
Diabetic foot ulcer (DFU), a complication of diabetes, is associated with an increased risk of major amputation and mortality. However, the underlying pathogenesis of DFU remains unclear. The goal of this study was to investigate the role and underlying mechanism of MAF bZIP transcription factor G (MAFG) in DFU wound healing.
Jiasi Huang, Ye Peng, Yihui Xiao, Yan Wang, Fangxing Hu
Checked
1 hour 33 minutes ago
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