Canadian Journal of Diabetes

A Systematic Evaluation of Canadian Diabetes Smartphone Applications for people with Type 1, Type 2 and Gestational Diabetes


1 month 1 week ago

1) Review diabetes apps available in Canada using the Mobile App Rating Scale (MARS) tool and generate usability scores for each 2) Characterize availability of features across all apps 3) Evaluate clinical safety of bolus insulin calculators 4) Evaluate quality of exportable blood glucose reports meant for HCP use.
Mary Nguyen, Nafis Hossain, Rohin Tangri, Jay Shah, Payal Agarwal, Fiona Thompson-Hutchison, Ilana Halperin

Association between systolic blood pressure and cardiovascular inpatient cost moderated by peer-support intervention among type 2 diabetes: two cohorts study


1 month 1 week ago

People with type 2 diabetes and increased systolic blood pressure (SBP) are at high risk of cardiovascular diseases (CVD). We aimed to investigate the association between CVD related hospital payments and SBP and test whether it is influenced by diabetes peer-support.
Dahai Yu, Yamei Cai, Jonathan Graffy, Daniel Holman, Zhanzheng Zhao, David Simmons

Greater nutritional risk scores in 2-year old children exposed to gestational diabetes mellitus in utero and their relationship to HOMA-IR at age 5-years


1 month 2 weeks ago

Exposure to gestational diabetes mellitus (GDM) in utero may impact nutritional intake and lifestyle habits in early childhood. However, it is unclear if nutritional status predicts greater risk for metabolic disturbances, such as insulin resistance (IR). The primary objectives were (1) to determine parent-reported nutritional risk scores in 2-year old children born to women with and without GDM, and (2) to assess whether these scores predict IR in 5-year old children.
Barkha P. Patel, Samantha S. McLellan, Anthony J. Hanley, Ravi Retnakaran, Jill K. Hamilton

Mental Health in Diabetes: Never a Better Time


1 month 2 weeks ago

We present this special issue of the Canadian Journal of Diabetes at a very unusual time in all of our lives. Not only has the COVID-19 pandemic had an impact on populations worldwide, the mortality and health-related consequences of this disease have been magnified in some communities over others, specifically for individuals with diabetes. Clearly, we are living through a global crisis that not only affects our health and mental health, but also has disrupted the economy, education and employment.
Michael Vallis, Tricia Tang, Gerri Klein

To Titrate or Not to Titrate: Factors influencing inpatient insulin management by residents and medical students


1 month 4 weeks ago

The day-to-day management of diabetes is often the responsibility of resident physicians in teaching hospitals, yet studies have consistently shown that learners lack confidence and knowledge of inpatient insulin titration. We sought to elucidate factors that influence inpatient management of diabetes by medical learners. We predicted that there would be conscious and unconscious variables at play, and we sought to determine the process by which learners arrived at insulin titration decisions.
Laura Hinz, Ronald J. Sigal, Elizabeth Oddone Paolucci, Kevin McLaughlin

Overexpression of the Severe Acute Respiratory Syndrome Coronavirus-2 Receptor, Angiotensin-Converting Enzyme 2, in Diabetic Kidney Disease: Implications for Kidney Injury in Novel Coronavirus Disease 2019


2 months ago

Diabetes is associated with adverse outcomes, including death, after coronavirus disease 19 (COVID-19) infection. Beyond the lungs, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the etiologic agent of the COVID-19 pandemic, can infect a range of other tissues, including the kidney, potentially contributing to acute kidney injury in those with severe disease. We hypothesized that the renal abundance of angiotensin-converting enzyme (ACE) 2, the cell surface receptor for SARS-CoV-2, may be modulated by diabetes and agents that block the renin-angiotensin-aldosterone system (RAAS).
Richard E. Gilbert, Lauren Caldwell, Paraish S. Misra, Kin Chan, Kevin D. Burns, Jeffrey L. Wrana, Darren A. Yuen

The severity of cardiovascular autonomic neuropathy is a predictor associated with major adverse cardiovascular events in patients with type 2 diabetes mellitus: A six-year follow-up study


2 months 1 week ago

Cardiovascular autonomic function impairment has been reported in patients with type 2 diabetes mellitus (T2DM) associated with cardiovascular (CV) events. We test the hypothesis that the severity of cardiovascular autonomic neuropathy (CAN) is a predictor associated with subsequent three-point major adverse cardiovascular events (three-P MACE) (combined endpoint of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke).
Yun-Ru Lai, Chih-Cheng Huang, Hsueh-Wen Chang, Wen-Chan Chiu, Nai-Wen Tsai, Ben-Chung Cheng, Jung-Fu Chen, Cheng-Hsien Lu

Exploring the Outcomes of a Pilot Education Program Tailored for Adults With Type 2 Diabetes and Mental Illness in a Community Mental Health Care Setting


2 months 3 weeks ago

People with mental illness and type 2 diabetes are more likely to experience diabetes complications than the general population. Diabetes management can be improved with tailored lifestyle intervention content. The purpose of this pilot study was to investigate diabetes insights of mental health-care patients after participation in a tailored education intervention.
Adriana Cimo, Desmond Loong, Carolyn S. Dewa

Diabetes Distress in Adults Living With Type 1 and Type 2 Diabetes: A Public Health Issue


2 months 4 weeks ago

The concept of chronic disease distress is not new. Many chronic health conditions, including cancer, lung disease, chronic pain, inflammatory bowel disease and others, come with significant emotional and psychological burden. In the diabetes world, there has been sufficient scientific study into distress such that that it is possible to demonstrate its importance as a public health issue and to propose system changes that could serve to benefit not only diabetes but other chronic illnesses. This is an important topic of examination as diabetes rates are climbing quickly and significant rates of diabetes distress are following (1–6).
Lisa deMolitor, Margaret Dunbar, Michael Vallis

Association Between Gestational Diabetes and Mental Illness


2 months 4 weeks ago

The rates of both gestational diabetes mellitus (GDM) and mental illness in pregnancy are rising. There is an association between type 2 diabetes and major depressive disorder, anxiety and schizophrenia, thus there is a need for greater understanding of the relationship between GDM and mental illness. This review suggests that there is a bidirectional and complex relationship between antenatal depression, gestational diabetes and postpartum depression. The combined effect of both a history of depression and gestational diabetes significantly increases the risk of postpartum depression.
Lauren Riggin

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