1 month ago
Pediatric obesity affects over 1.5 million Canadian youth and few interventions have proven success for weight management. Little is known about the efficacy of adding Dialectical Behaviour Therapy (DBT) for improving adherence to lifestyle change and biopsychosocial health of adolescents living with obesity. The aim of this pilot trial was to address this gap.
JANA SLAGHT, MAE SANTOS, MANDY ARCHIBALD, LAURENCE KATZ, BRANDY WICKLOW, TRACIE AFIFI, JONATHAN MCGAVOCK
1 month ago
People experiencing socioeconomic disadvantages face barriers to attending diabetes education appointments. We aimed to determine whether there are differences in initial attendance to a tertiary diabetes education centre by referral location or neighbourhood measures of socioeconomic deprivation.
SAANIA TARIQ, TODD WILSON, WENHUA ZHANG, SASHA WIENS, DAVID CAMPBELL
1 month ago
Routine use of continuous glucose monitoring (CGM) and the data it provides can improve hemoglobin A1C in type 2 diabetes (T2D) compared to capillary glucose monitors. Through understanding factors that influence engagement with CGM technology, its use can be optimized. The purpose was to examine the impact of engagement with CGM technology and virtual coaching on A1C in T2D. This sub-study followed a quantitative correlational design conducted in London, ON. Participants completed an A1C at baseline and at 3 months, and were asked to attend 1 virtual class every 2 weeks and 1 phone check-in on alternating weeks.
NELLIE BORDIGNON, DANIEL HENKE, SONJA REICHERT
1 month ago
Type 1 diabetes (T1D) affects ∼300,000 Canadians, due to autoreactive T lymphocytes against insulin-producing beta cells. However, the precise triggers are not well understood. Environmental factors influencing gut microbiota impact T1D autoimmunity by stimulating autoreactive T cells, as the microbiome interfaces dietary nutrients, host immune system, and metabolic profiles. Early exposure to maternal influences shapes the gut microbiome, making the perinatal/nursing periods critical intervention windows.
ALEJANDRO SCHCOLNIK-CABRERA, ERIN STRACHAN, LUISA PESSOA SOARES, XAVIER CLEMENTE-CASARES, SUE TSAI
1 month ago
Type 1 diabetes (T1DM) pregnancies have a 3% to 10% risk of developing diabetic ketoacidosis (DKA), which is an obstetrical emergency, resulting in fetal demise in up to 33% of episodes. Twenty per cent of DKA episodes in pregnancy occur at glucoses under 14 mmol/l, risking delayed diagnosis.
MEGAN MCQUISTON, PATRICIA URRUTIA, SIMRIT BRAR, SHELLEY BENDER, AMITA MAHAJAN, UMAIR SAJID, JAMIE BENHAM, XINYE SERENA WANG, LISA O'NEILL, PUNREET NIRWAN, LOIS DONOVAN
1 month ago
The present study evaluated the real-world effectiveness and tolerability of a single-pill combination of empagliflozin/linagliptin, in patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD).
SANJAY MAHAJAN
1 month ago
Chronic and lifestyle-related conditions present multidimensional challenges, necessitating evidence-based care plans tailored to individual preferences, motivations, and perspectives. Research has demonstrated that implementing personalized care plans, integrating patient preferences, social determinants, and strong patient-provider relationships significantly enhances patient adherence and health outcomes. Nevertheless, an aging population and a diminishing, overburdened workforce impede the delivery of personalized, evidence-based care.
LOREEN WALES
1 month ago
Post Covid, the Gestational Diabetes Mellitus (GDM) ambulatory care clinic at the Queensway Carleton Hospital (QCH) faced significant program challenges due to the transition from virtual back to in-person clinics, high staff turnover, and a 50% increase in patient volume. Limited GDM patient feedback on clinic workflow processes and variable staff satisfaction over different care models further highlighted the need for a clinic program review. With safety grant support from Healthcare Insurance Reciprocal of Canada (HIROC), GDM patients and clinic staff were actively engaged in a comprehensive GDM program and clinic review for the purpose of enhancing patient safety by optimizing clinic flow and empowering GDM patients’ self-management skills.
CATHERINE MCCUMBER, AISHA ASAD AHMED, NISHA BAGUHIN, KIM FINCH, STACEY WHELAN, KAREN AFGHAN, CONNIE TUTTLE, DONI WHITE, LISA FERRIER-BOULT, DONNA MCGLENNON
1 month ago
Diabetes in pregnancy increases the risk of complications. This includes a higher risk of neonatal intensive care unit (NICU) admission, however, less is known about the predictors of NICU admission following gestational diabetes.
MITCHELL WILSON, JENNIFER YAMAMOTO, CHRISTY PYLYPJUK
1 month ago
Pediatric insulin pump starts are often done by diabetes educators at tertiary diabetes clinics. To meet high demand, we trialed partnering with industry to start pumps for patients >10 years old.
KAREN HENDERSON, LAUREL FRY, ELIZABETH CUMMINGS
1 month ago
Medication adherence can be a challenge for youth (10 to 18 years) with type 2 diabetes (T2D). We hypothesize that psychological and social factors affect medication adherence.
JOANNA ANKAMA, SARA SCHUR, ALLISON DART, ELIZABETH SELLERS, JONATHAN MCGAVOCK, MELISSA DEL VECCHIO, EDGAR DELBERT, STEPHANIE GOGUEN, BRANDY WICKLOW, LUCAS MOSIENKO, BRENDEN DUFAULT
1 month ago
Youth living with type 2 diabetes (T2D) have identified mental health as an important factor in diabetes management. Dialectical Behavior Therapy (DBT) is an evidence-based program that includes teaching mindfulness, emotion regulation, and distress tolerance. This pilot project examines the feasibility and tolerability of virtual DBT skills training as a mental health intervention in youth with T2D.
MELISSA DEL VECCHIO, LILY PANKRATZ, EMILY CAMERON, ELIZABETH SELLERS, JONATHAN MCGAVOCK, MANDY ARCHIBALD, LINDA DIFFEY, LAURENCE KATZ, TANYA DAWN MCDOUGALL, ALLISON DART, BRANDY WICKLOW
1 month ago
Maternal preconception obesity, excessive gestational weight gain, and adverse metabolic health increase the risk of childhood obesity in offspring, and adverse postpartum cardiometabolic health in mothers. It remains unknown whether preconception lifestyle interventions impact offspring health in childhood. Therefore, our study aims to compare lifestyle and cardiometabolic factors in 50 mothers and their 6–10-year-old children born in the Obesity-Fertility randomized controlled trial that compared a lifestyle intervention during preconception and pregnancy in women with obesity and infertility (IG) to usual fertility care (CG).
ALEXANDRA THIBODEAU, CHRISTOPHE RICHER DIT LAFLÈCHE, FARRAH JEAN-DENIS, SOREN HARNOIS-LEBLANC, PATRICE PERRON, MARIE-EVE MATHIEU, FRÉDÉRIC DALLAIRE, ANNE-SOPHIE MORISSET, MARTIN BROCHU, JEAN-PATRICE BAILLARGEON
1 month ago
Glucagon-like peptide 1 receptor agonists (GLP-1RA) are effective medications for type 2 diabetes mellitus (T2DM) and obesity, yet their uptake among patients most likely to benefit from them has been slow.
PRACHI RAY, JASON MOGGRIDGE, ALANNA WEISMAN, MINA TADROUS, DANIEL DRUCKER, BRUCE PERKINS, MICHAEL FRALICK
1 month ago
Cystic fibrosis-related diabetes (CFRD) and impaired glucose tolerance affect up to 50% of adults with CF. CFRD is associated with accelerated lung function decline and mortality, especially in women. A new CF mouse model (B6-Tg(CFTR508del)Cwr), expressing the human F508del cftr gene, is becoming available. We conducted a study to validate B6-Tg(CFTR508del)Cwr mice as a CFRD model.
DANIEL NEIRA AGONH, KAROLINA SADOWSKA, FREDERIC CHAPPE, VALERIE CHAPPE, YOUNES ANINI
1 month ago
People living with type 2 diabetes (PWT2D) face nutrition constraints that may impact their food-purchasing decisions. Using mixed-methods, we combined eye-tracking data and qualitative data to evaluate the decision-making process of PWT2D in a food retail setting. Participants aged 40–65 years were recruited, including a PWT2D study group and comparison group without T2D. Eligible participants were invited to McGill’s Retail Innovation Lab (RIL) to complete a shopping task. Participants purchased 4 food products from 3 different categories (salty, sweet, beverage, and a free choice among those 3), while wearing eye-tracking glasses.
PABLO ARRONA-CARDOZA, ANNE-SOPHIE BRAZEAU, DAIVA NIELSEN
1 month ago
Type 2 diabetes (T2D) affects 9% of Canadians. Indigenous peoples in Canada face higher T2D incidence and poorer outcomes compared to non-Indigenous individuals. Implicit and explicit biases towards Indigenous Peoples and people with T2D in health care have been documented, impacting the quality of care they receive. This study evaluated biases of 79 health-care practitioners (HCPs) in the Interior Health region of British Columbia towards Indigenous peoples and their explicit attitudes towards people with T2D.
RENEE YOUNG, MARY E. JUNG, REBECCA REITSMA, KYRA BRAATEN
1 month ago
Avoiding Diabetes After Pregnancy Together with Moms (ADAPT-M) is a nutrition and physical activity coaching program that targets modifiable risk factors for type 2 diabetes among women with a history of gestational diabetes mellitus (GDM). Evidence indicates that postpartum lifestyle modification can prevent diabetes after GDM, and a pilot randomized trial showed high feasibility, uptake, and satisfaction with the program. Thus, pre-implementation strategies are underway to implement the program at 3 settings in Ontario, Canada.
KATELYN SUSHKO, DIANA SHERIFALI, LORRAINE L. LIPSCOMBE
1 month ago
Understanding the relationship between circulating biomarkers and body composition measurements is crucial to improve the prediction of health outcomes after weight loss intervention. This study aims at identifying independent biomarkers associated with 6 body composition measurements from bioimpedance (namely trunk fat mass [FM], arm FM, leg FM, trunk fat-free mass [FFM], arm FFM, and leg FFM) among a panel of 1,463 circulating biomarker levels measured using the Proximity Extension Assay (PEA) technology, in a subset of 50,673 adult individuals of European descent from the UK Biobank.
DEJVIT HAMZARAJ, JAMES FEINER, KEONA PANG, GUILLAUME PARE, MARIE PIGEYRE
1 month ago
There is a need to assess the impact of virtual care in diabetes in pregnancy (DIP) clinics given a recent increase in virtual care use. The objective of this study was to compare maternal and neonatal outcomes between individuals with gestational diabetes (GDM) treated with virtual care versus standard in-person care. A retrospective cohort study was performed of individuals with GDM that attended interdisciplinary DIP clinics in Calgary between 2017–2022. The primary exposure was visit modality for the initial appointment with a diabetes educator.
SAMIN DOLATABADI, JENNIFER YAMAMOTO, ERIN BRENNAND, LOIS DONOVAN, JAMIE BENHAM
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