1 month ago
Diabetes registries have recently grown in prevalence to survey, monitor, and consolidate patient data. Registries are becoming more patient-focused (patient-led, patient-operated, or patient-accessed) to support diabetes management. Through this scoping review, we aimed to understand the goals, purpose, and context for diabetes registries defined as patient-focused and how patients are involved, engaged, and utilize these registries.
LANA MOAYAD, PAIGE ALLISTON, SAIRA KHALID, DONNA FITZPATRICK-LEWIS, HERTZEL GERSTEIN, DIANA SHERIFALI
1 month ago
Type 2 diabetes (T2D) has significant morbidity if not managed effectively. This study aimed to quantify the total health benefits costs and investigate differences in short- and long-term disability (STD and LTD) claims between employees with T2D versus those without prediabetes or T2D in Canadian employer-sponsored benefit plans. We examined a self-insured health benefit plan database of over 170,000 employees and dependents in Canada. Our study focused on 34,889 employee claimants aged 40–59 years from July 1, 2022 – June 30, 2023, including 3,575 with T2D (T2D cohort) and 31,314 without prediabetes or T2D (non-T2D cohort).
SCOTT CAMPBELL, GODFREY MAU, JULIE HVIID HAHN-PEDERSEN, CHRIS VON HEYMANN
1 month ago
Reduced beta-cell mass and function associated with islet inflammation is a key defect in type 2 diabetes (T2D). Amyloid formation, due to aggregation of human islet amyloid polypeptide (hIAPP; amylin), contributes to islet inflammation and beta-cell failure in T2D, but the mechanisms are unclear. We assessed the content of (pro)hIAPP and its aggregates in extracellular vesicles (EVs) released from non-diabetic and T2D islets, as a potential mechanism.
RUSHIE TYAGI, JANESSA SAWATZKY, LUCY MARZBAN
1 month ago
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have heart and kidney benefits for patients with type 2 diabetes and cardiovascular disease (CVD). We aimed to describe the potential effects of prior authorization/step therapy (PA/ST) and relatively high income-based deductibles compared to regular benefit status on SGLT2i prescriptions. Despite identical formular indications, SGLT2i access policies are different in Alberta (PA/ST, modest co-pay), Manitoba (PA/ST, relatively high income-based deductible), and Ontario (regular benefit status, modest co-pay).
MEGAN MCCREARY, ROSEANNE YEUNG, DONNA MANCA, MICHELLE GREIVER, ALEXANDER SINGER, DARREN LAU
1 month ago
Internalizing the stigma associated with homelessness can inhibit one's motivation to engage in self-care. This is especially problematic when one has diabetes, a chronic illness that requires consistent effort to avoid potentially devastating complications. The aim of our study is to describe the essence of the phenomena of stigma and shame felt by people with lived experience of homelessness and diabetes (PWLEHD). In addition, we are exploring which coping methods appear to lead to greater shame resilience for this population.
MATT LARSEN, DAVID CAMPBELL
1 month ago
The objective of our systematic review and meta-aggregation was to synthesize women's suggestions to improve prenatal gestational diabetes (GDM) care, as guided by the lived patient experience.
YUYANG JULIANNE FENG, ZHIDI DENG, ALLISON SIVAK, ROSEANNE YEUNG, TANIYA NAGPAL
1 month ago
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1 month ago
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are effective medications for type 2 diabetes mellitus (T2DM) and obesity, yet their uptake among patients most likely to benefit has been slow.
Prachi Ray, Jason A. Moggridge, Alanna Weisman, Mina Tadrous, Daniel J. Drucker, Bruce A. Perkins, Michael Fralick
1 month 1 week ago
Bridie Hamilton, Lisa-Marie Williams, Gurleen Gill, Maya Liepert, Juanita Wilzer, Ali Ladak, Elisabeth Oliviero, Annie Garon-Mailer, Cathy J. Sun
1 month 2 weeks ago
Individuals living with diabetes are often hospitalized. Despite this, little is known about their experiences with hospital care. In this study we examined the comprehensive experiences of patients hospitalized due to diabetes in Alberta, Canada, and compared them with those of patients hospitalized for other chronic conditions.
Kyle A. Kemp, Paul Fairie, Maria J. Santana
1 month 2 weeks ago
Whereas marginal food insecurity has been recognized as important in Canadian food security policy, the category of marginal food security (MFS) is often ignored in US food security research.
Angela D. Liese, Emmanuel F. Julceus, Andrea D. Brown, Catherine Pihoker, Edward A. Frongillo, Katherine A. Sauder, Faisal S. Malik, Anna Bellatorre, Beth A. Reboussin, Jason A. Mendoza
1 month 3 weeks ago
Gestational diabetes mellitus (GDM) is a common pregnancy complication. Studies have shown that the prevalence of GDM is rising worldwide. In this study we aimed to describe the prevalence of GDM in Ontario, Canada, between 2015 and 2021.
Hardil A. Bhatt, Gillian L. Booth, Ghazal Fazli, Calvin Ke, Chris Kenaszchuk, Lorraine L. Lipscombe, Sarah Mah, Laura C. Rosella, Deva Thiruchelvam, Baiju R. Shah
2 months ago
Jeremy Gilbert MD FRCPC
2 months ago
The United Kingdom Prospective Diabetes Study (UKPDS) established the importance of glycemic management to reduce the risk of long-term complications in people with type 2 diabetes [1]. More recently, clinical trials have demonstrated that certain glucose-lowering medications can reduce cardiac and renal complications of diabetes in certain populations, beyond the effects of glucose lowering alone. We conducted a thorough review of the existing evidence to support people living with type 2 diabetes and their health-care providers in the selection of glucose-lowering agents.
Diabetes Canada Clinical Practice Guidelines Expert Working Group, Baiju R. Shah, Harpreet S. Bajaj, Sonia Butalia, Kaberi Dasgupta, Dean T. Eurich, Rahul Jain, Karen Leung, Kerry Mansell, Scot Simpson
2 months ago
Diabetes Canada prepares clinical practice guidelines to provide a synthesis of the best evidence to help clinicians in their daily practice. Evidence-based medicine seeks to integrate the best evidence with clinical expertise and the values of people living with diabetes. It is a challenging process to balance the goals of providing guidelines based on high-quality evidence with addressing the needs of clinicians who commonly face clinical scenarios for which there is no robust evidence.
Diabetes Canada Clinical Practice Guidelines Expert Working Group, Sonia Butalia, Harpreet S. Bajaj, Rahul Jain, Karen Leung, Kerry Mansell, Sonja M. Reichert, Peter Senior, Baiju R. Shah
2 months ago
2 months ago
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