Canadian Journal of Diabetes

The Effects of Continuous Glucose Monitoring on Patient-Reported Outcomes in Adults with Non-Insulin Dependent Type 2 Diabetes: A Randomized Controlled Trial


1 week 3 days ago

Assess the effect of a 6-week continuous glucose monitor (CGM) intervention with telemonitoring-enabled virtual diabetes educator visits on patient-reported outcomes (PROs) in adults with type 2 diabetes (T2D) not using insulin.
Inga Olu-Jordan, Pratima Singh, Jiawei Ryan Zheng, Roseanne O. Yeung, Donna P. Manca, Tawnya Perry, Gulelala Rahim, Evan Hagen, Darren Lau

Safety and Effectiveness of Subcutaneous Insulin for Management of Mild to Moderate Diabetic Ketoacidosis in Non-Pregnant Patients: A retrospective cohort study at a tertiary care centre


1 week 6 days ago

Subcutaneous (SC) insulin has been studied as an alternative to intravenous (IV) insulin to reduce resource consumption in the management of diabetic ketoacidosis (DKA). However, the feasibility and safety of an SC protocol has not been demonstrated in a Canadian context.
Judy K. Qiang, Alex Kiss, Wanqing Yu, Andre Carlos Kajdacsy-Balla Amaral, Dominick Shelton, Lowyl Notario, Ilana Halperin

“It’s a chronic, vicious, cycle”: diabetes health professionals’ perceptions of the impact of knee osteoarthritis on type 2 diabetes management


3 weeks 4 days ago

Type 2 diabetes (T2D) and knee osteoarthritis (OA) frequently co-occur, and concomitant knee OA increases risk for diabetes complications. Despite this, OA is frequently undertreated. Diabetes health professionals’ (HPs’) perceptions of the impact of knee OA in people with T2D may impact how it is addressed in clinical practice. We aimed to understand how diabetes HPs perceive the impact of knee OA on diabetes management and outcomes.
Joy Du, Esther J. Waugh, Rebecca Voth, Crystal MacKay, Ian Stanaitis, Gillian A. Hawker, Lorraine L. Lipscombe, Lauren K. King

Postpartum Diabetes Screening and Conversion Rates Among Women Diagnosed with Gestational Diabetes Mellitus Using Standard versus Modified Criteria During the COVID-19 Pandemic


4 weeks ago

To examine postpartum diabetes screening and rates in women diagnosed with gestational diabetes mellitus (GDM) using standard versus modified criteria during the COVID-19 pandemic.
Sonia Butalia, Olesya Barrett, Anamaria Savu, Vichy Liyanage, Peter Senior, Roseanne O. Yeung, Padma Kaul

Psychosocial Experiences of Adolescents with Type 2 Diabetes: A Systematic Review and Meta-Synthesis


1 month ago

Globally, the prevalence of Type 2 Diabetes (T2D) among adolescents is increasing. While T2D is known to bring physical health challenges, less is known about adolescents’ psychosocial experiences of T2D. We aimed to identify and synthesize existing qualitative research about adolescents’ psychosocial experiences of T2D to inform healthcare recommendations.
Melissa Oxlad, Lorraine Smith, Tyla McNamara, Ashley Young, Ella Borrowdale, Alexia Pena

Patterns in the Incidence (1994–2018) and Prevalence (2004–2018) of Type 1 and Type 2 Diabetes Among Nova Scotian Youth Under 20 Years of Age


1 month 1 week ago

Rates of type 1 and type 2 diabetes (T1D and T2D, respectively) in youth may be increasing globally, but findings vary across populations. We aimed to determine changes in incidence and prevalence of T1D and T2D over a 25-year period (1994–2018) in youth <20 years of age in Nova Scotia (NS).
Elizabeth A. Cummings, Teresa Pinto, O. Maya Rao, Pamela Talbot

Identifying Potential Sustainable and Scalable Interventions to Recognize Signs of Diabetes in Children Across Canada


1 month 2 weeks ago

Delayed diagnosis of diabetes in children can lead to diabetic ketoacidosis, a life-threatening condition occurring in 10% to 80% of children at diabetes diagnosis. Ketoacidosis is preventable with prompt recognition of signs, urgent attendance to care, and rapid diagnosis and management. Our aim in this study was to plan for the development of an intervention to recognize signs of diabetes in children and prevent ketoacidosis that is evidence and theory informed and has potential for widespread implementation and long-term impact across Canada.
Zeenat Ladak, Priscilla Medeiros, Geneviève Rouleau, Jennifer Shuldiner, Shazhan Amed, Elizabeth Cummings, Manpreet Doulla, Josephine Ho, Mark Inman, Sarah E. Lawrence, Patricia Li, Elizabeth Moreau, Meranda Nakhla, Julia Von Oettingen, Elizabeth Sellers…

The Role of Group Exercise Classes as a Source of Motivation and Support for Those With Diabetes---a Silver Bullet?


1 month 3 weeks ago

Physical activity (PA) is a critical component of diabetes management, resulting in lower glycated hemoglobin (A1C) levels [1,2] and reduced risk of complications and comorbidities [3,4]. Despite this, most people living with diabetes do not meet current guidelines [5,6]. Although adherence to regular PA is challenging across all populations, those with diabetes may face specific barriers toward PA adoption and maintenance. Notably, these barriers may also vary according to diabetes type, as individuals who have type 1 or type 2 diabetes (T1D and T2D, respectively) may experience unique challenges.
Lindsay S. Nagamatsu, Joyla A. Furlano, Samantha Marshall, Olivia Ghosh-Swaby, Gillian Rutherford, Jane Yardley

Physician-reported Pediatric Diabetes Virtual Visit Quality and Outcome Not Associated With Social Determinants of Health


2 months 3 weeks ago

Social determinants of health (SDH) impact diabetes outcomes. In response to the COVID-19 pandemic, virtual care ensured health care access. However, socially disadvantaged groups have less technology access and skills, leading to potential disparities. We assessed the association between SDH and virtual visit success in children living with diabetes.
Laurence Bastien, Ellen B. Goldboom, Ewa Sucha, Richard J. Webster, Ivan Terekhov, Caroline Zuijdwijk

Assessment of Clinical Factors Influencing Glucose Management Indicator and Glycated Hemoglobin Discordance in Children With Type 1 Diabetes: A 1-Year, Real-world Data Observation


2 months 3 weeks ago

Published data still highlighted discordances between glucose management indicator (GMI; the parameter estimating glycated hemoglobin [A1C] from continuous glucose monitoring [CGM] reporting) and laboratory A1C, for reasons yet to be explored. In our study we aimed to identify potential clinical factors contributing to these discordances.
Grażyna Deja, Aleksandra Brudzińska, Łukasz Wybrańczyk, Rafał Deja, Przemysława Jarosz-Chobot

Can a Combined Epigenetic-Biomarker Score Supplant Chronologic Age as an Independent Determinant of Incident Death in Adults With Dysglycemia


3 months ago

Diabetes and prediabetes are associated with premature death and are recognized as conditions of accelerated biologic aging. To date, the best measurement of biologic age is chronologic age. Measures of biologic age that can replace chronologic age as a predictor of death can better approximate risk in affected individuals.
Hertzel C. Gerstein, Guillaume Pare, Keyun Zhou, Serena Yang, Michael Chong, Gregory R. Steinberg, Shun Fu Lee

A diabetes peer mentorship program for First Nations youth and young adults: An intervention protocol


3 months 1 week ago

The rising incidence of type 2 diabetes (T2D) among Indigenous peoples, exacerbated by historical injustices and health inequities, underscores the need for culturally-sensitive health interventions that address both the physiological and psychological burdens of diabetes. This research protocol describes a community-driven initiative aimed at enhancing diabetes management among Indigenous youth and young adults in Canada, leveraging the lived experience and leadership of Indigenous young adults.
Sahar Fazeli, Jonathan Linton, Paul Linton, Lucy Trapper, Catherine Godin, Helene Porada, Deborah Da Costa, Kaberi Dasgupta, Isabelle Malhame, Claudia Mitchell, Elham Rahme, Julia Elisabeth Von Oettingen, Romina Pace

Multidisciplinary Lifestyle Intervention in a Clinical Setting Leads to Remission of Type 2 Diabetes, Prediabetes, and Early Insulin Resistance


3 months 1 week ago

Trials using intensive lifestyle interventions have demonstrated remission of type 2 diabetes mellitus (T2DM), but data on real-world clinical approaches remain limited.
Christopher Gudas-Cantin, Valérie Dionne, Élise Latour, Karine Lamoureux, Lyne Chevrefils, Chantal Gariepy, Marie-Hélène Morissette C, Lina Mokdad, Juliette Morin, Sarah-Maude Martin, Mathieu Gayda, Florent Besnier, Sara Desmarais, Anil Nigam, Philippe L…

In the Eye of Controversy: A Deeper Look Into the Impact of Glucagon-like Peptide 1 Receptor Agonists on Diabetic Retinopathy and Nonarteritic Anterior Ischemic Optic Neuropathy


3 months 2 weeks ago

Glucagon-like peptide 1 receptor agonists (GLP1-RAs), a relatively new class of drugs, are used widely in treating type 2 diabetes mellitus and obesity. Maintaining long-term glycemic control lowers the risk of development and progression of diabetic retinopathy. However, recent literature has raised concerns about transient worsening of the condition with use of GLP1-RAs. In this review we evaluate the association between GLP1-RAs and retinopathy in patients with diabetes mellitus. We also analyzed the available evidence on the potential association between semaglutide therapy and nonarteritic anterior ischemic optic neuropathy (NAION).
Nadia Nadeem, Raghad Mazin Al Issa, Asnin Shah, Rahaf Wardeh, Fauzia Rashid, Elamin Ibrahim Abdelgadir, Alaaeldin Bashier

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