Canadian Journal of Diabetes

Self-management group education to reduce fear of hypoglycaemia as a barrier to physical activity in people living with type 1 diabetes: A pilot randomised controlled trial.

6 days 19 hours ago

To evaluate the feasibility, acceptability, and preliminary efficacy of a theory-driven, group education intervention designed to reduce fear of hypoglycaemia (FoH) as a barrier to physical activity (PA) in adults with type 1 diabetes (T1D).
Marian C. Brennan, Matthew A. Albrecht, Janie A. Brown, Gavin D. Leslie, Nikos Ntoumanis

Circulating miR-148a-5p and miR-21-5p as novel diagnostic biomarkers in Egyptian male patients with metabolic syndrome

2 weeks 1 day ago

Metabolic syndrome (MetS) is a group of abnormalities related to metabolism that increase the risk of cardiac diseases, type 2 diabetes and mortality. MicroRNAs (miRs) act as regulators of many cellular and metabolic events and any dysregulation of these tiny molecules cause a great disturbance in patient's health state.
Ahmed S. Doghish, Ahmed M. Elsisi, Ashrraf I. Amin, Ahmed I. Abulsoud

“A touch of sugar”: The impact of health beliefs on diabetes self-management among Black Canadians. A qualitative study

1 month ago

Black Canadians have higher rates of diabetes and complications compared to White Canadians. However, research on diabetes self-management in this community is lacking. We conducted a qualitative study to explore diabetes self-management in the Black Canadian community using the lens of the Health Belief Model.
Rukia M. Swaleh, Catherine Yu

The effect of diabetes health coaching on glycemic control and quality of life in adults living with type 2 diabetes: a community-based randomized controlled trial.

1 month 2 weeks ago

Providing frequent telephone-based DHC and access to DE to adults living with T2DM for one year supports improvements in glycemic control and quality of life.
Diana Sherifali, Anka Brozic BPHE, Pieter Agema, Zubin Punthakee, Natalia McInnes, Daria O’Reilly, R. Muhammad Usman Ali, Sarah Ibrahim, Hertzel C. Gerstein

Prevalence and Correlates of Positive Mental Health Among Canadian Adults with Type 1 or Type 2 Diabetes: Results from the Canadian Community Health Survey- Mental Health

1 month 2 weeks ago

Current definitions of mental health are no longer limited to presence or absence of mental illness. Although dimensions of mental illness have been well studied among people with diabetes, little is known about positive mental health. Optimal positive mental health is referred to as flourishing and is characterized by happiness, psychological well-being, and social well-being. Therefore, the purpose of this study was to examine the prevalence and correlates of flourishing mental health among Canadian adults diagnosed with diabetes.
R.J. Burns, K. Fardfini

Prevalence and risk Evaluation of Diabetic complications of the foot among Adults with type 1 and type 2 diabetes in a Large Canadian population (PEDAL study)

1 month 2 weeks ago

The lower limb complications of diabetes contribute significantly to patient morbidity and healthcare costs in Canada. Despite practice guidelines, awareness of, and screening for, modifiable early pathologies has been inconsistent. The study objective was to determine the prevalence and types of early foot pathologies among a large, Canadian, community care-based diabetes population.
Ronnie Aronson, Lisa Chu, Nicole Joseph, Ruth Brown

Insulin edema associated with newly diagnosed Type 1 Diabetes and high A1C: A case and review of the pediatric literature

1 month 3 weeks ago

Insulin edema is a rare and poorly understood complication of insulin therapy. It has been associated with the initiation of insulin in patients with newly diagnosed diabetes or the intensification of insulin therapy in those with poor glycemic control. This condition is rarely reported in pediatric patients. We describe a case of insulin edema in a 14-year-old male with potential risk factors of very elevated hemoglobin A1c (A1C) at diagnosis and history of unilateral renal atrophy. We also present a discussion of the pathophysiology of this condition and a review of the pediatric literature.
Noor Sawalha, Hannah Geddie

Thiamine-Responsive Megaloblastic Anemia-Related Diabetes: Long-Term Clinical Outcomes in 23 Pediatric Patients From the DPV and SWEET Registries

1 month 3 weeks ago

To describe clinical presentation and long-term outcomes in a large cohort of children diagnosed with thiamine-responsive megaloblastic anemia (TRMA)-related diabetes.
Katharina Warncke, Nicole Prinz, Violeta Iotova, Desiree Dunstheimer, Nicolin Datz, Beate Karges, Mallikarjun V. Jali, Dorothea Linsenmeyer, Birthe Susanne Olsen, Monika Seiwald, Priya Prahalad, Gideon de Sousa, Danièle Pacaud, SWEET and DPV Study Groups

Effect of Empagliflozin and Liraglutide on the Nucleotide-Binding and Oligomerization Domain-Like Receptor Family Pyrin Domain-Containing 3 Inflammasome in a Rodent Model of Type 2 Diabetes Mellitus

1 month 4 weeks ago

Chronic inflammation has been identified as an important driver of cardiovascular disease in type 2 diabetes (T2D) and can lead to a higher risk of cardiovascular events and rehospitalization. Empagliflozin or liraglutide represent 2 classes of drugs with proven efficacy in the treatment of T2D to reduce macrovascular complications; however, the exact mechanism behind their cardioprotective properties remains incompletely understood. The nucleotide-binding and oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is implicated in the progression of cardiovascular disease and linked to the progression of cardiovascular risk factors, such as T2D.
Mark Gordon, Patrick Meagher, Kim A. Connelly

3 hours 8 minutes ago
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