Canadian Journal of Diabetes
Insomnia and Cardiometabolic Health: Bridging the Sleep Deficit to Disease Prevention
Insomnia a condition marked by difficulty initiating or maintaining sleep, or early morning awakenings despite an adequate opportunity for adequate rest. It affects up to one-third of adults, with around 10% meeting the criteria for insomnia disorder. Emerging research increasingly points to insomnia as a significant, modifiable risk factor for cardiometabolic diseases, including type 2 diabetes, cardiovascular disease, chronic kidney disease, and metabolic dysfunction-associated steatotic liver disease (MASLD).
“Letter To Editor: Temporal trends in the rates of foot complications and lower extremity amputation related to type 1 and 2 diabetes in adults in selected Canadian provinces”
Virtual vs. In-Person Care in Gestational Diabetes Management: A Retrospective Cohort Analysis
The rising prevalence of gestational diabetes (GDM) presents a challenge to healthcare systems. Virtual care has emerged as a potential solution to alleviate this burden, but limited data exist on its effectiveness. This study evaluated maternal and neonatal outcomes in individuals with GDM managed with virtual care versus in-person care.
A retrospective analysis of postpartum glucose testing incidence by prenatal care provider specialty in a Canadian gestational diabetes cohort.
Gestational diabetes mellitus (GDM) increases future risks of type 2 diabetes and cardiovascular disease. Despite Diabetes Canada guidelines recommending postpartum glucose testing following GDM, uptake remains low. Canadian population-based studies are needed to examine systems-level factors affecting uptake.
Association between circulating vitamin C concentrations and risk of diabetes mellitus: dual evidence from NHANES database and Mendelian randomization analysis
This study explores the link between circulating vitamin C levels and the risk of diabetes mellitus (DM) using data from the National Health and Nutrition Examination Survey (NHANES) for the cycles of 2003-2004, 2005-2006, and 2017-2018. Our analysis revealed a significant inverse relationship, showing that higher levels of vitamin C are associated with a reduced risk of DM. Specifically, higher vitamin C concentrations correlated with lower odds of DM, particularly at elevated quartile levels. Despite these findings, Mendelian randomization (MR) analysis did not establish a causal link between vitamin C and type 1 diabetes (T1DM).
Uptake and Factors Associated with COVID-19 Vaccination Among 3,779,733 Adults Living With and Without Diabetes: A Population Cohort Study in a Universal Health Care Setting
People with diabetes are vulnerable to health inequities and population level COVID-19 vaccine uptake among adults with diabetes is unknown. Our aim was to assess COVID-19 vaccine uptake among adults with and without diabetes and the factors associated with vaccination.
“I Don’t Want to Feel Judged”: A Qualitative Study of Adolescents’ Experiences of Living with Type 2 Diabetes
To explore adolescents' experiences of T2D, particularly concerning (1) diagnosis and management and (2) emotional wellbeing.
Confronting Type 2 Diabetes in South Asians of the Greater Toronto Area: Turning the tide.
The South Asian population is rapidly growing in the Greater Toronto Area with a growth rate of 10.6% versus the national average of 5.2%. Diabetes disproportionately affects South Asians, 8.1 times higher compared to Caucasians with increased risk of macrovascular and microvascular complications. There are several risk factors that have been identified including 24 single nucleotide polymorphisms, higher insulin resistance, low mean skeletal mass with higher visceral fat, and socioeconomic and family stressors.
Evaluation of efforts to support students with Type 1 Diabetes in Ontario schools: survey of parents
Children and youth with type 1 diabetes (T1D) must have support to manage their condition at school. In 2017, Ontario students and their parents were surveyed to assess the level of school support and the extent to which that support met perceived needs. In 2018 a provincial policy was established, providing high level guidance regarding children with T1D in school. We redistributed our survey in 2023 to determine whether support for children with T1D has improved and where gaps remain.
Temporal trends in the rates of foot complications and lower-extremity amputation related to type 1 and 2 diabetes in adults in selected Canadian provinces
To determine the contemporary annual incidence rates of hospitalization for diabetes-related foot complication (DFC) and lower-extremity amputation in Canada.
Loss of MAF bZIP transcription factor G restores ATG7/BECN1-mediated autophagy to inhibit ferroptosis and improve angiogenesis in diabetic foot ulcer wound healing
Diabetic foot ulcer (DFU), a complication of diabetes, is associated with an increased risk of major amputation and mortality. However, the underlying pathogenesis of DFU remains unclear. The goal of this study was to investigate the role and underlying mechanism of MAF bZIP transcription factor G (MAFG) in DFU wound healing.
A Square Peg in a Round Hole: Social Experiences of Living With Diabetes in Canada in 2024
Diabetes self-management often occurs in social contexts, around others without diabetes. International consensus identifies the pervasive presence of social stigma toward those with diabetes, negatively impacting health, well-being, and social and professional lives. In this study we aimed to identify the social experiences of Canadian adults living with type 1 diabetes (T1D) or type 2 diabetes (T2D).
"Managing Type 1 Diabetes During Marathons: A Case Study on Glucose Monitoring and Technology Failures"
Gestational Diabetes Laboratory Testing in Alberta Before and During the COVID-19 Pandemic
There are high-quality data demonstrating improved pregnancy outcomes with gestational diabetes mellitus (GDM) treatment [1]. Thus, screening for and treatment of GDM is recommended by clinical practice guidelines around the world [2]. Although controversy remains regarding the optimal screening recommendations, both who should be screened and which glucose test and level cut-offs should be used, most international guideline recommendations include dynamic glucose testing, such as the 75- or 100-g oral glucose tolerance test (OGTT) with or without a preceding 50-g glucose challenge [3].
Preparing a New Generation of Providers in Canada: The Mental Health + Diabetes Training Program
Diabetes care in Canada is compromised by the lack of resources to adequately address the mental health challenges associated with both type 1 and type 2 diabetes. To address this gap Breakthrough T1D (formerly JDRF) Canada and Diabetes Canada developed a bilingual training program, and associated directory listing successful graduates, to educate and empower existing mental health providers to better provide services to those living with diabetes. This study reports on the development and initial outcomes of this virtual training program.
Response
Khan et al have responded to our recent publication on the development of a patient-reported outcome measure to assess the impact of continuous glucose monitoring (CGM) devices on diabetes self-management [1]. The authors have raise several important issues regarding our work. First, they noted that all data on the impact of CGM use on capability, opportunity, and motivation to self-manage diabetes are self-report data. Importantly, as stated by the authors, self-report is subject to social desirability bias.
Cannabis Hyperemesis Syndrome Can Mimic Diabetic Gastroparesis in Cannabis Users With Type 1 Diabetes
A 51-year-old woman with type 1 diabetes, hypertension, and hypothyroidism visited the emergency department (ED) with excessive nausea and vomiting. At presentation, her serum glucose was 28.5 mmol/L, glycated hemoglobin (A1C) was 8.0%, and beta-hydroxybutyrate was 4.2 mmol/L (normal 0.6 mmol/L), with an increased anion gap of 18.8 mEq/L (normal 4 to 12 mEq/L). Arterial blood gas showed that pH was 7.53 and bicarbonate was 18.6 mEq/L. Urine drug screen was positive for cannabis. Past medical history was notable for type 1 diabetes for 12 years with mild diabetic retinopathy.
Associations of Systemic Immune-Inflammation Index With Mortality Risk Among Adults in Diabetic Kidney Disease, NHANES 1999 to 2018
Immune-inflammation plays a crucial role in the pathogenesis of diabetic kidney disease (DKD), but an exact assessment of indicators remains undefined. In this study we address the link between systemic immune-inflammation index (SII) and mortality risk in DKD, and we explore the effect of sex disparities.
What Is the Effectiveness of Type 2 Diabetes–related Patient Decision Aids? Secondary Analysis of a Systematic Review
Patient decision aids (PtDAs) are evidence-based interventions to help people faced with difficult health-care decisions. Little is known about their effectiveness in people facing diabetes-related decisions. The aim of this study was to evaluate the scope and effectiveness of diabetes-related PtDAs for screening, prevention, and treatment decisions.
Canadian Journal of Diabetes RSS feed.
Subscribe to Canadian Journal of Diabetes feed