20 hours 23 minutes ago
Obesity and aging are associated with increased activity of the innate immune system. This chronic systemic inflammation contributes to the development of type 2 diabetes and long-term complications and is partly driven by the activation of the NLRP3 inflammasome. We conducted a comparative analysis of clinical parameters, non-esterified fatty acid (NEFA) profiles, immune cell subsets, and inflammatory responses of peripheral blood mononuclear cells obtained from both healthy individuals and those diagnosed with type 2 diabetes.
Joyce de Paula Souza, Justus S. Fischer, Karine Jeanneau, Cyril Allard, Eline Angevaare, Dominik Aschenbrenner, Ursula Bodendorf, Benjamin Demarco, John S. Gounarides, Saskia Killmer, Jiri Kovarik, Sabina Pfister, Hong Yin, Vithushan Ratnarasa, Marianne…
6 days 20 hours ago
Patient-centered care is a hallmark of family medicine, and patient-centered care for diabetes has been associated with better outcomes. The Primary Care Diabetes Support Program (PCDSP) in London, Ontario, uses a patient-centered model of care and targets three groups of patients at high risk for diabetes complications: 1) medically complex, 2) socially complex, and 3) those without a primary care provider. We describe, from the patient’s perspectives, how the PCDSP operationalizes patient-centered care.
Gillian Young, Anika Garg, Dana Ryan, Leslie Meredith, Stewart Harris, Sonja M. Reichert, Lindsay Hedden, Maria Mathews
1 week 2 days ago
Muhammad Tabish, Hamna Khan, Muhammad Naveed
2 weeks 1 day ago
Krishna Jaipal, Sanjana Bebu Punshi, Mehak Kumari Bansari
2 weeks 2 days ago
Masashi Hasebe, Chen-Yang Su
4 weeks ago
Shorrem Naeem, Zainab Arif
1 month ago
Ontario listed SGLT-2 inhibitors (SGLT2i) as regular public drug benefits for adults age ≥ 65, while other Canadian provinces providing benefits for SGLT2i implemented special authorization restrictions. We hypothesized that special authorization led to lower SGLT2i use among older adults with diabetes and cardiovascular disease (CVD) in other provinces (Alberta, Manitoba, New Brunswick, and Saskatchewan), compared to Ontario.
Darren Lau, Douglas C. Dover, Hena Qureshi, Roseanne O. Yeung, Dean Eurich, Peter Senior, Sonia Butalia, Padma Kaul
1 month ago
To assess the feasibility and acceptability of a patient navigator (PN) in a pediatric type 1 diabetes (T1D) clinic.
Elise Schlissel Tremblay, Ashley B. Tartarilla, Kali McCollister, Mia Umali, Melicia Y. Whitley, Julia Ainsworth, Patrice Melvin, Lori M. Laffel, Valerie L. Ward
1 month ago
Adolescents and young adults (AYA) often report feeling poorly prepared and dissatisfied with the process of transitioning from pediatric to adult type 1 diabetes (T1D) care. We aimed to examine the impact of Bridging the Gap (BTG), an audit and feedback-based intervention, on transition care.
Syed Zain Ahmad, Noah Ivers, Ian Zenlea, Baiju R. Shah, Peter C. Austin, Cheril Clarson, Jennifer Harrington, Alanna Landry, Geetha Mukerji, Zubin Punthakee, Mark R. Palmert, Janet Parsons, Mikayla Sonnenberg, Rayzel Shulman
1 month 1 week ago
Angela Y. Kim, James Hanley, Rebecca Fuhrer, Charles de Mestral
1 month 1 week ago
Syed Aaraiz Ul Hassan, Krishna Jaipal Lohana, Shorrem Naeem
1 month 1 week ago
To compare severe hypoglycemia and all-cause mortality between insulin regimens in people with type 2 diabetes on insulin.
Reid H. Whitlock, Zach Raizman, David Collister, Katherine J. Bernier, Sarah M. Sigurdson, Navdeep Tangri, Clara Bohm, Claudio Rigatto, Paul Komenda, Jennifer M. Yamamoto
1 month 1 week ago
We investigated hypertension control (<130/80 mmHg) among individuals with diabetes, use of first-line antihypertensive medications, and physician responses to uncontrolled blood pressure (BP) measurements (i.e. repeat measurements and medication intensification).
Sachin V. Pasricha, Lisa Dubrofsky, Bailey Goldman, Laura O’Driscoll, Huijuan Yang, Shane Golden, Brad Millson, Sheldon W. Tobe
1 month 2 weeks ago
Syed Aaraiz Ul Hassan, Noor Ul Huda, Noor Un Nisa
1 month 2 weeks ago
Syeda Kashaf Batool, Fatima Asif, Muhammad Owais
1 month 2 weeks ago
Muhammad Husnain Ahmad, Muhammad Bilal, Muhammad Ibrahim, Hafiza Iman
1 month 2 weeks ago
the article by Dolatabadi et al. offers timely insights into the use of virtual care in managing gestational diabetes mellitus (GDM), but several critical limitations temper the strength and applicability of its conclusions. This Letter to the Editor outlines concerns regarding the study’s retrospective design, its omission of patient-reported and adherence-related outcomes, and its limited generalizability. Drawing on recent literature, including evaluations aligned with the Quadruple Aim and meta-analyses of digital interventions, we argue for more robust and patient-centered methodologies in future research.
Muhammad Khubaib Iftikhar
1 month 3 weeks ago
Rongrong Chen, Lin Sheng, Xiaohan Zhang
1 month 3 weeks ago
Unstable housing and homelessness are associated with increased risks of diabetes-related morbidity and mortality. Concordantly, as few as 12-30% of people with lived experience of homelessness (PWLEH) complete recommended screening for microvascular complications of diabetes. Innovative models of care delivery are needed to address this disparity. We recently piloted a novel, community-based, point-of-care screening program for diabetes complications (the SAFER model of care, i.e. Screening for glycosylated hemoglobin (A1c), feet, eyes and renal function) in Calgary, Alberta.
Hannah M. Yaphe, Sara Scott, Huanghe Ding, Breanna McSweeney, Eshleen Grewal, David JT. Campbell
2 months 2 weeks ago
The publisher regrets that Supplementary Material failed to be published with this article and is now included. The publisher apologizes for any inconvenience caused.
Ilana J. Halperin, Brandy Wicklow, Shazhan Amed, Alanna Chambers, Charlotte Courage, Elizabeth Cummings, Patricia Kirkland, Dylan MacKay, Meranda Nakhla, Zubin Punthakee, Paul M. Ryan, Lindsay Sawatsky, Peter A. Senior, Bikrampal S. Sidhu, Alanna Weisman…
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2 hours 37 minutes ago
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