Real-world impact of type 2 diabetes mellitus in employer-sponsored benefit plans
To quantify the health benefit costs associated with type 2 diabetes mellitus (T2D) among employees aged 40-59 years in Canadian employer-sponsored benefit plans.
Canadian Journal of Diabetes
“It’s a chronic, vicious, cycle”: diabetes health professionals’ perceptions of the impact of knee osteoarthritis on type 2 diabetes management
Type 2 diabetes (T2D) and knee osteoarthritis (OA) frequently co-occur, and concomitant knee OA increases risk for diabetes complications. Despite this, OA is frequently undertreated. Diabetes health professionals’ (HPs’) perceptions of the impact of knee OA in people with T2D may impact how it is addressed in clinical practice. We aimed to understand how diabetes HPs perceive the impact of knee OA on diabetes management and outcomes.
Postpartum Diabetes Screening and Conversion Rates Among Women Diagnosed with Gestational Diabetes Mellitus Using Standard versus Modified Criteria During the COVID-19 Pandemic
To examine postpartum diabetes screening and rates in women diagnosed with gestational diabetes mellitus (GDM) using standard versus modified criteria during the COVID-19 pandemic.
Psychosocial Experiences of Adolescents with Type 2 Diabetes: A Systematic Review and Meta-Synthesis
Globally, the prevalence of Type 2 Diabetes (T2D) among adolescents is increasing. While T2D is known to bring physical health challenges, less is known about adolescents’ psychosocial experiences of T2D. We aimed to identify and synthesize existing qualitative research about adolescents’ psychosocial experiences of T2D to inform healthcare recommendations.
Patterns in the incidence (1994-2018) and prevalence (2004-2018) of type 1 and type 2 diabetes among Nova Scotian youth under 20 years
Rates of type 1(T1D) and type 2(T2D) diabetes in youth may be increasing globally; however, findings vary across populations. We aimed to determine changes in incidence and prevalence of T1D and T2D over a 25-year period (1994-2018) in youth under age 20 in Nova Scotia(NS).
Identifying Potential Sustainable and Scalable Interventions to Recognize Signs of Diabetes in Children Across Canada
Delayed diagnosis of diabetes in children can lead to diabetic ketoacidosis, a life-threatening condition occurring in 10-80% of children at diabetes diagnosis. Ketoacidosis is preventable with prompt recognition of signs, urgent attendance to care, and rapid diagnosis and management. The objective of this study was to plan for the development of an intervention to recognize signs of diabetes in children and prevent ketoacidosis, that is evidence and theory-informed and has potential for widespread implementation and long-term impact across Canada.
Predicting the risk of COVID-19 among adult patients with diabetes: A machine learning approach
To develop a machine learning model that accurately predicts the risk of acquiring COVID-19 in community-dwelling adults with type 1 and/or type 2 diabetes in Alberta, Canada.
The role of group exercise classes as a source of motivation and support for those with diabetes – a silver bullet?
Physician-reported pediatric diabetes virtual visit quality and outcome not associated with social determinants of health
Social determinants of health (SDH) impact diabetes outcomes. In response to COVID-19, virtual care ensured healthcare access. However, socially disadvantaged groups have less technology access and skills, leading to potential disparities. We assessed the association between SDH and virtual visit success in children living with diabetes.
The assessment of clinical factors influencing Glucose Management Indicator and Hba1c discordance in children with type one diabetes – one-year real-world data observation.
Published data still highlighted discordances between GMI (parameter estimating HbA1c from CGM report) and laboratory HbA1c, with reasons yet to be explored. This study aimed: to identify potential clinical factors contributing to these discordances.
Can a Combined Epigenetic-Biomarker Score Supplant Chronologic Age as an Independent Determinant of Incident Death in Adults with Dysglycemia
Diabetes and prediabetes are associated with premature death and are recognized as conditions of accelerated biologic aging. To date, the best measurement of biologic age is chronologic age. Measures of biologic age that can replace chronologic age as a predictor of death can better approximate risk in affected individuals.
A diabetes peer mentorship program for First Nations youth and young adults: An intervention protocol
The rising incidence of type 2 diabetes (T2D) among Indigenous peoples, exacerbated by historical injustices and health inequities, underscores the need for culturally-sensitive health interventions that address both the physiological and psychological burdens of diabetes. This research protocol describes a community-driven initiative aimed at enhancing diabetes management among Indigenous youth and young adults in Canada, leveraging the lived experience and leadership of Indigenous young adults.
Multidisciplinary Lifestyle Intervention in a Clinical Setting Leads to Remission of Type 2 Diabetes, Prediabetes, and Early Insulin Resistance
Trials using intensive lifestyle interventions have demonstrated remission of type 2 diabetes mellitus (T2DM), but data on real-world clinical approaches remain limited.
Ten-fold Insulin Icodec Overdose: A Case Report
In The Eye Of Controversy: A Deeper Look Into The Impact Of Glucagon-Like Peptide 1 Receptor Agonists (GLP1RA) on Diabetic Retinopathy and Non-arteritic anterior ischemic optic neuropathy (NAION)
Glucagon-like peptide 1 receptor agonists (GLP1RA), a relatively new class of drugs, are widely used in treating type 2 diabetes mellitus and obesity. Maintaining long-term glycemic control lowers the risk of development and progression of diabetic retinopathy. However, recent literature has raised concerns about transient worsening of the condition with GLP1RA use.
“Letter to the Editor: The association between insulin regimen and the risk of severe hypoglycemia and mortality in adults with type 2 diabetes. A large population-based retrospective cohort study”
Blood characteristics of patients with type 2 diabetes and response of their peripheral blood mononuclear cells to inhibitors of the NLRP3-inflammasome and caspase-1
Obesity and aging are associated with increased activity of the innate immune system. This chronic systemic inflammation contributes to the development of type 2 diabetes and long-term complications and is partly driven by the activation of the NLRP3 inflammasome. We conducted a comparative analysis of clinical parameters, non-esterified fatty acid (NEFA) profiles, immune cell subsets, and inflammatory responses of peripheral blood mononuclear cells obtained from both healthy individuals and those diagnosed with type 2 diabetes.
Patient perspectives of the operationalization of adult patient-centered care at the Primary Care Diabetes Support Program, London, Ontario: A Qualitative Descriptive Study
Patient-centered care is a hallmark of family medicine, and patient-centered care for diabetes has been associated with better outcomes. The Primary Care Diabetes Support Program (PCDSP) in London, Ontario, uses a patient-centered model of care and targets three groups of patients at high risk for diabetes complications: 1) medically complex, 2) socially complex, and 3) those without a primary care provider. We describe, from the patient’s perspectives, how the PCDSP operationalizes patient-centered care.
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